Meeting Report Hamburg 2005
2nd Workshop “Recombination and Repair”, Hamburg 16.-17. September 2005
The 2nd workshop on “Recombination and Repair” of the DGDR was held in Hamburg at 16-17. September 2005 (organised by Jochen Dahm-Daphi and Kerstin Borgmann).
We had, as before in Munich , 22 oral presentations (15 min + 5 min discussion) covering three topics. (1) Immunoglobulin rearrangement, (2) homologous mitotic recombination and (3) Non-homologous endjoining. For all three topics three first class keynote speakers gave an overview about most relevant recent discoveries. Jean-Marie Buerstedde, (Inst. of Mol Radiobiol,GSF, Neuherberg) talked about the connection of immunoglobulin rearrangement, hypermutation and hyperrecombination and its major genetic player AID (activation induced cytidine deaminase). Ulrich Pannike (Ulm University, Dep.of Hematology) reported on their findings about Artemis and its role in V(D)J recombination and NHEJ. Isabelle Plo (CEA, Fontenay-aux-roses, France) discovered a new role of the AKT1 protein kinase controling homologous recombination and NHEJ. As before, results for most of the currently studied model systems were reproted namely E coli, yeast, arabidopsis, chicken, mouse and human, which underlines the broad spectrum of activities within the German DNA repair research. Both genetic impact of quite a number of genes such as Rad6, Rad18, PCNA, Rad50, Nbs1, RecQ, recG, MutS, MPH1, Rad51, XRCC3 and the various genes of the endjoining pathways, as well as repair mechanisms were extensively discussed.
We had participants from 6 different countries, which was certainly only possible using English as regular conference language. We feel that our decision in 2003 to hold all the DNA repair meetings in English was wise and timely. As before, the meeting attracted advanced principal investigators as well as graduate students and all felt to benefit from this workshop with its high level science and relaxed atmosphere. The idea to establish the recombination meeting as a regular biannual meeting was welcomed. The next host for 2007 will be Georg Iliakis in Essen.
Jochen Dahm-Daphi and Kerstin Borgmann
Deutsch
Englisch 